Diabetes, Insulin Resistance and Body Composition

Completed

• Conditions: Insulin Resistance, Diabetes

• Registration Number: NCT06724068
• Lead Sponsor: Xuan Song

Brief Summary

The goal of this retrospective study is to learn about the correlation between diabetes, insulin resistance and body compositions.

The main question\[s\] it aims to answer are:

* \[The difference of body composition between the individuals of insulin resistance and diabetes\]

* \[The effect of diabetes on body composition\]

Detailed Description

Not available

Study Timeline

• Study Start: 2021-12-17
• Primary Completion: 2022-08-31
• Study Completion: 2022-08-31
• Status Verified: 2024-12
• Study First Submitted: 2024-12-03
• Study First Submitted QC: 2024-12-06
• Last Update Submitted: 2024-12-07
• Study First Posted: 2024-12-09
• Last Update Posted: 2024-12-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 515

Inclusion Criteria

1. Adults aged 18 years and older.
2. Diagnosed with type 2 diabetes mellitus according to recognized diagnostic criteria.
3. Availability of complete body composition data (e.g., DXA measurements).
4. Documented HbA1c levels and other glycemic control data.
5. Continuous medical records available during the study period

Exclusion Criteria

1. Presence of other severe metabolic diseases, such as liver failure or kidney failure.
2. Use of medications affecting muscle mass (e.g., glucocorticoids) for more than three months.
3. History of malignancy or ongoing treatment for cancer.
4. Missing critical research data (e.g., diabetes duration or HbA1c levels).
5. History of surgeries causing significant body composition changes (e.g., bariatric surgery).

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Prevalence of Sarcopenia in Diabetic Patients	Retrospective analysis of data collected between2019 and 2022	The proportion of diabetic patients diagnosed with sarcopenia, assessed based on measurements of muscle mass, muscle strength, and physical performance. Sarcopenia will be defined according to AWGS 2019 and EWGSOP2

Trial Locations

Locations (1)

The First Affiliated Hospital of Shandong First Medical University; 🇨🇳 Jinan, Shandong, China