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The effect of vitamin C on lymphocyte apoptosis induced by radiatio

Phase 2
Conditions
Patients treated with ablation in cardiac electrophysiology studies.
Atrial fibrillation and flutter, Paroxysmal tachycardia
Registration Number
IRCT2016072529068N1
Lead Sponsor
Vice chancellor for research, Shiraz University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
30
Inclusion Criteria

Non-smoking; Lack of infectious disease; Do not use of antibiotics; Unexposed to ionizing radiation, 24 hours prior to sampling
Exclusion criteria: Use of multivitamins; Use of alcohol; Acute or chronic disease

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Apoptosis. Timepoint: Before the intervention and after intervention within 24 hours after the test. Method of measurement: Counting the number of apoptotic peripheral blood lymphocytes by flow cytometry.
Secondary Outcome Measures
NameTimeMethod
Bax protein. Timepoint: Before intervention and after intervention within 24 hours after the test. Method of measurement: Counting the number of Bax protein by ELISA method.;Bcl-2 protein. Timepoint: Before intervention and after intervention within 24 hours after the test. Method of measurement: Counting the number of Bcl-2 protein by ELISA method.
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