Evaluation of Hemodynamic and Ventilatory Effects of Negative Pressure Ventilation

Recruiting

• Conditions: Cardiac Output, Low

• Registration Number: NCT06088966
• Lead Sponsor: Karlsburg Hospital

Brief Summary

Investigation of the effects of negative pressure ventilation after cardiac surgery in adults onto performance of the left and right heart and the lungs.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-08-01
• Status Verified: 2023-10
• Study First Submitted: 2023-10-03
• Study First Submitted QC: 2023-10-11
• Last Update Submitted: 2023-10-11
• Study First Posted: 2023-10-18
• Last Update Posted: 2023-10-18
• Primary Completion: 2024-01-01
• Study Completion: 2024-04-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• patients with pulmonary artery catheter after cardiac surgery

Exclusion Criteria

• minimally invasive surgery
• unstable conditions
• bleeding
• unability to fit cuirass

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Stroke Volume Index in ml/m2	1 hour

Secondary Outcome Measures

Name	Time	Method
tricuspid annular plane systolic excursion in mm	1 hour	measured via transesophageal echocardiography
right ventricular ejection fraction in %	1 hour	measured via pulmonary catheter
blood pressure in mm/Hg	1 hour
right ventricular fractional area change in %	1 hour	measured via transesophageal echocardiography
Vena contract of tricuspid valve in mm	1 hour	measured via transesophageal echocardiography
Heart rate in beats/min	1 hour
end diastolic volume index in ml/m2	1 hour	measured via pulmonary catheter
Cardiac index in l/min/m2	1 hour	measured via pulmonary catheter
arterial oxygen saturation in %	1 hour
mixed venous oxygen saturation in %	1 hour	measured via pulmonary catheter

Trial Locations

Locations (1)

Klinikum Karlsburg, Klinik für Anästhesiologie; 🇩🇪 Karlsburg, Mecklenburg Vorpommern, Germany