Physiological Stress 15O-H2O Total-body PET/CT protocol
- Conditions
- coronary artery disease10011082myocardial perfusion
- Registration Number
- NL-OMON53400
- Lead Sponsor
- ucleaire Geneeskunde en Moleculaire Beeldvorming
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 20
o Healthy subjects:
* Aged above 40 years
* Male or female
* Good general health
* Height 1.60 m - 1.85 m
* BMI 20-25 kg/m2
* Informed consent signed
o Patients suspected or known with Coronary Artery Disease:
* Aged above 40 years
* Male or female
* Height 1.60 m - 1.85 m
* Diagnosed or suspected with Coronary Artery Disease
* Informed consent signed
o Healthy subjects:
* Clinical history of diabetes, hypertension, dyslipidemia
* History of cardiac disease
* Family history of Coronary Artery Disease
* Active or short history of cigarette smoking
* Inability or unwillingness to give informed consent
* Known hypersensitivity to adenosine
* Clinical active bronchospasm
* Chronic obstructive pulmonary disease or asthma
* Chronic kidney disease
* Expressed willing to not continue with the participation
* Pregnancy or breastfeeding
* Claustrophobia
* Not able to cycle
o Patients suspected or known with Coronary Artery Disease:
* Known hypersensitivity to adenosine
* Bundle branch block
* Presence or temporal or definitive pacemaker
* Presence of heart valve prosthesis, shoulder prosthesis, prosthetic
reconstruction of the chest
wall or other prosthetic devices within the field of view
* Clinical active bronchospasm
* Chronic obstructive pulmonary disease or asthma
* Expressed willing to not continue with the participation
* Pregnancy or breastfeeding
* Claustrophobia
* Not able to cycle
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method