MedPath

Physiological Stress 15O-H2O Total-body PET/CT protocol

Conditions
coronary artery disease
10011082
myocardial perfusion
Registration Number
NL-OMON53400
Lead Sponsor
ucleaire Geneeskunde en Moleculaire Beeldvorming
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
20
Inclusion Criteria

o Healthy subjects:
* Aged above 40 years
* Male or female
* Good general health
* Height 1.60 m - 1.85 m
* BMI 20-25 kg/m2
* Informed consent signed

o Patients suspected or known with Coronary Artery Disease:
* Aged above 40 years
* Male or female
* Height 1.60 m - 1.85 m
* Diagnosed or suspected with Coronary Artery Disease
* Informed consent signed

Exclusion Criteria

o Healthy subjects:
* Clinical history of diabetes, hypertension, dyslipidemia
* History of cardiac disease
* Family history of Coronary Artery Disease
* Active or short history of cigarette smoking
* Inability or unwillingness to give informed consent
* Known hypersensitivity to adenosine
* Clinical active bronchospasm
* Chronic obstructive pulmonary disease or asthma
* Chronic kidney disease
* Expressed willing to not continue with the participation
* Pregnancy or breastfeeding
* Claustrophobia
* Not able to cycle

o Patients suspected or known with Coronary Artery Disease:
* Known hypersensitivity to adenosine
* Bundle branch block
* Presence or temporal or definitive pacemaker
* Presence of heart valve prosthesis, shoulder prosthesis, prosthetic
reconstruction of the chest
wall or other prosthetic devices within the field of view
* Clinical active bronchospasm
* Chronic obstructive pulmonary disease or asthma
* Expressed willing to not continue with the participation
* Pregnancy or breastfeeding
* Claustrophobia
* Not able to cycle

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath