Comparison of the effect of PRP versus PRP plus gonadotropin and gonadotropin alone on ovarian rejuvenation in patients with diminished ovarian reserve
Phase 2
- Conditions
- Ovarian rejuvenation in diminished ovarian reserve patients.Primary ovarian failureE28.3
- Registration Number
- IRCT20151013024512N7
- Lead Sponsor
- Deputy of Research and Development, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 45
Inclusion Criteria
Female infertility
Diminish ovarian reserve (AMH<1.1 and AFC< 5-7)
20 to 48 years
Exclusion Criteria
Uterin anomaly
Polycystic Ovarian Syndrome
Male factor
Tubal factor
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Increase Anti-Müllerian hormone level. Timepoint: At the beginning of the study, every month up to 3 months. Method of measurement: Lab Test.
- Secondary Outcome Measures
Name Time Method Antral follicular count. Timepoint: 1 to 4 months later. Method of measurement: Transvaginal sonography.;Spontaneous pregnancy. Timepoint: 3 months later. Method of measurement: Lab test.;Entering assisted reproductive cycle. Timepoint: Once the AMH increases or the patient insists on doing assisted reproductive cycle. Method of measurement: Lab test.