Effects of Intermittent Theta Burst Stimulation in Addition to Constraint-Induced Movement Therapy in Stroke Patients
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Stroke, Ischemic
- Sponsor
- Istanbul Medeniyet University
- Enrollment
- 15
- Locations
- 1
- Primary Endpoint
- Wolf-Motor Function Test
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
In recent studies, it has been reported that intermittent theta-burst stimulation (iTBS) provides additional benefits when applied in adjunct to the rehabilitation in all stages of stroke (acute, subacute, or chronic). In our study, it was aimed to evaluate the effectiveness of iTBS applied in addition to modified constraint-induced movement therapy (mCIMT). By doing so, we intend to increase patient adherence to neurorehabilitation and decrease the cost of rehabilitation.
Investigators
Esma Nur KOLBAŞI
Researcher
Istanbul Medeniyet University
Eligibility Criteria
Inclusion Criteria
- •First time and unilateral stroke
- •1-12 months after the incident
- •Getting 24 points or more in Mini Mental Status Examination
- •Being able to stand for 2 minutes without any help by using the upper extremity as a support tool when necessary.
- •Being a low-functioning patient according to the CIMT criteria: a) At least 10 degrees of active wrist extension starting from the angle of full flexion, b) 10 degrees of extension at the metacarpophalangeal and inter-phalangeal joints of at least 2 fingers
Exclusion Criteria
- •those who score more than 2.5 points on the Motor Activity Log-28 scale,
- •who have severe pain in the upper extremity (5 and above on the Visual Analogue Scale) and spasticity (3 and above on the Modified Ashworth Scale), which may affect the treatment, and
- •Those who do not have adequate communication skills.
- •Patients who have visual problems
Outcomes
Primary Outcomes
Wolf-Motor Function Test
Time Frame: 45 minutes
It is a new time-based method to evaluate upper extremity performance while providing insight into joint-specific and total limb movements
Fugl-Meyer Assessment-Upper extremity
Time Frame: 30 minutes
The Fugl-Meyer Assessment (FMA) is a stroke-specific, performance-based impairment index. It is designed to assess motor functioning, balance, sensation and pain.
Secondary Outcomes
- Motor Evoked Potentials (MEPs)(10 minutes)