Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity

Completed

• Conditions: Crohn Disease; Dermatomyositis; Graves Disease; Myasthenia Gravis; Uveitis; Addison Disease; Sjögren Syndrome; Takayasu Arteritis; Ulcerative Colitis; SCAD

• Registration Number: NCT03941184
• Lead Sponsor: Mayo Clinic

Brief Summary

This case control study aims to determine whether spontaneous coronary artery dissection (SCAD) is associated with autoimmune diseases and to update the incidence of SCAD in a population-based cohort.

Detailed Description

Not available

Study Timeline

• Study Start: 1995-01-01
• Study First Submitted: 2019-04-01
• Study First Submitted QC: 2019-05-03
• Study First Posted: 2019-05-07
• Status Verified: 2020-11
• Primary Completion: 2020-11-10
• Study Completion: 2020-11-10
• Last Update Submitted: 2020-11-20
• Last Update Posted: 2020-11-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 114

Inclusion Criteria

• Adults age 18 to 110
• Residence in Olmsted County. Note: if sufficient numbers cannot be reached using only Olmsted County, will expand to the 27-county region.

Exclusion Criteria

• None

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Odds of autoimmune disease in SCAD cases compared to controls	Through study completion, or approximately 50 years (average age of study participants)
Incidence Rate of SCAD	Through study completion, or approximately 50 years (average age of study participants)

Secondary Outcome Measures

Name	Time	Method
SCAD recurrence	Through study completion, or approximately 50 years (average age of study participants)

Trial Locations

Locations (1)

Mayo Clinic; 🇺🇸 Rochester, Minnesota, United States