Spinal Epidural Lipomatosis: a Case Report and Review of the Literature

Completed

• Conditions: Spinal Stenosis

• Registration Number: NCT04622501
• Lead Sponsor: Canadian Memorial Chiropractic College

Brief Summary

Introduction Lumbar spinal epidural lipomatosis (SEL) is a rare condition defined by an excessive deposition of adipose tissue in the lumbar spinal canal. The objective of this case report is to document a clinical case of SEL presenting within a multidisciplinary spine clinic and to compare our clinical findings and management with the current literature.

Case presentation A 51-year-old female presented at a spine clinic with low back pain, bilateral leg pain and difficulty walking. MR imaging of the lumbar spine showed L4-L5 and L5-S1 degenerative disk disease with evidence of severe central canal stenosis due to extensive epidural lipomatosis. The patient was initially advised to lose weight, undergo a course of physiotherapy, and consult with the pain clinic. Because of lack of improvement, the patient was scheduled for L4-S1 posterior spinal decompression and L4-L5 posterior spinal instrumented fusion.

Discussion The discussion will include the diagnosis of SEL, imaging appearance, its risk factors, etiology and management.

Conclusion This case report describes a case of lumbar spinal stenosis due to SEL with neurological symptoms. Some risk factors have also been identified in the literature. MRI is considered as the reference standard for its diagnosis. The therapeutic approach of patients with SEL is not standardized. Thus, reporting and investigating the diagnostic process and treatment of this patient will positively contribute to better management for other future patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-06-10
• Primary Completion: 2019-06-11
• Study Completion: 2020-06-10
• Study First Submitted: 2020-08-10
• Status Verified: 2020-11
• Study First Submitted QC: 2020-11-03
• Study First Posted: 2020-11-10
• Last Update Submitted: 2020-11-10
• Last Update Posted: 2020-11-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1

Inclusion Criteria

• Adults patient with a clinical diagnosis of Spinal Epidural Lipomatosis (MRI and clinical diagnosis)

Exclusion Criteria

• Absence of clinical diagnosis of Spinal Epidural Lipomatosis

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Low back pain	1 year after surgery	Visual Pain Scale (0-10)
Distance walking	1 year after surgery	Distance walking (meter)
Distance Walking	6 weeks after surgery	Distance walking (meter)

Trial Locations

Locations (1)

CMCC; 🇨🇦 Toronto, Ontario, Canada