Effect of Specific Diet and Circuit-based Exercise on Weight and/or Fat Loss
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Obesity
- Sponsor
- Slovak Academy of Sciences
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- A Body weight change after specific weight loss intervention
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
The main purpose of this study is to assess metabolic effects (decreased amount of body fat content, insulin sensitivity and lipid profile improvement) of weight loss intervention based on specific life style counseling (low calorie "metabolic stairs" diet and circuit-based exercise in a comparison to conventional diet and exercise. The main hypothesis is that more significant beneficial metabolic effects will have specific life style counseling effect than conventional diet and exercise. The main purpose of this study is to assess above mentioned metabolic changes before and after 6-8 weeks of weight loss intervention.
The investigators will also study the following:
- The impact of life style counseling induced weight and/or fat loss on physical fitness
- The impact of life style counseling induced weight and/or fat loss on metabolic parameters (e.g. insulin sensitivity, lipid profile, ect.)
Detailed Description
I
Investigators
Adela Penesova, MD, PhD
Biomedical Center of Slovak Academy of Sciences, Institute of clinical and translational research
Slovak Academy of Sciences
Eligibility Criteria
Inclusion Criteria
- •Healthy Volunteers
- •BMI≥25 kg/m2
Exclusion Criteria
- •Thyroid disease
- •Chronic diseases(rheumatic,liver, kidney, pulmonary, etc. diseases) have current signs or symptoms of severe, progressive or uncontrolled renal, hepatic, hematologic, gastrointestinal, endocrine, pulmonary, cardiac, neurologic, or cerebral disease, or diabetes;
- •chronic infections
- •show evidence of malignancy
- •be women who are pregnant, nursing
- •medical treatment except allergy medicines
- •tobacco, alcohol or drug addiction
Outcomes
Primary Outcomes
A Body weight change after specific weight loss intervention
Time Frame: 8 weeks
To assess the body composition changes (fat-free mass and fat mass (in kg)).
Secondary Outcomes
- Metabolic parameters(8 weeks)