Role of Dietary Protein in a Familiar Breakfast Meal on Subjective Satiety, Food Intake and Thermic Effect of Food in Normal Weight and Overweight/Obese Children
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 17
- 试验地点
- 2
- 主要终点
- 1a) Ad libitum food intake (in kcal)
研究概览
简要总结
Objectives: To determine the effect of protein content of familiar breakfast meals on subjective appetite, food intake (FI), glycemic response and Thermic Effect of Food (TEF) in normal weight (NW) and overweight (OW)/obese (OB) children.
Specific Objectives:
1a.To determine the effect of familiar breakfast meals (450 kcal containing eggs and varying in protein content (15, 30, and 45g) on subjective appetite, glycemic response and food intake at a test meal 4 h later in NW and. OW/OB children.
1b. To describe the effect of isocaloric (450 kcal) familiar breakfasts either high in protein (optimal protein from Objective 1a) or low in protein on TEF and substrate utilization over 5 h in NW and OW/OB children.
详细描述
Hypothesis
The investigators hypothesize that increasing the high-quality protein content of a breakfast meal will dose dependently increase subjective satiety, lower FI and glycemic response, and increase the TEF in both NW and OW/OB children.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 9 Years 至 14 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Boys and girls between the ages of 9 and 14 y
- •Only peri-pubertal girls
- •Normal body weight (between the 5th and 85th BMI percentile for age and gender)
- •OW/OB (>85th BMI percentile for age and gender)
排除标准
- •Food sensitivities
- •Food allergies
- •Dietary restrictions
- •Health, learning, emotional or behavioural problems
- •On any medication
结局指标
主要结局
1a) Ad libitum food intake (in kcal)
时间窗: Four hours after breakfast
次要结局
- 1b) The thermic effect of a high versus low protein meal(Resting energy expenditure (REE) at baseline and up to five hours post test meal)
- Subjective Appetite(Assessed every 15 min for 4 h)
- Blood glucose response(Measures at 15, or 60 min intervals for 4 h)
研究者
Nick Bellissimo
Assistant Professor and Director, Food Intake Regulation & Satiety
Toronto Metropolitan University