The Impact of Text Messaging on Medication Adherence and Exercise Regimen Among Post-myocardial Infarction Patients

Not Applicable

Completed

• Conditions: Myocardial Infarction
• Interventions: Behavioral: Text message reminder for medication adherence; Behavioral: Text message reminder for exercise regimen

• Registration Number: NCT02783287
• Lead Sponsor: Brigham and Women's Hospital

Brief Summary

The purpose of this study is to assess the impact of text message reminders on adherence to medications and exercise in patients recently discharged from the hospital after a myocardial infarction (MI).

Detailed Description

The Impact of Text Messaging on Medication Adherence and Exercise Regimen among Post-Myocardial Infarction Patients includes two single-center randomized control trials to assess the impact of text message reminds on adherence to medications and exercise regimen in patients recently discharged from the hospital after MI.

Recruitment conducted at Cambridge Cardiac Rehabilitation in Ontario, Canada for both the medication adherence and exercise trial. Potential study subjects are evaluated for inclusion and exclusion criteria, give written informed consent, and are randomized, in a 1:1 ratio, to either intervention or usual care (control).

Patients randomized to the intervention arm in the medication adherence trial receive an automated text message once per day at the time they are prescribed to take their medication. The text message does not contain any personal or pharmacological information.

Patients randomized to the intervention arm in the exercise adherence trial receive four text messages per day at 7:30 am, 12:00 pm, 6:00 pm, and 9:00 pm, reminding them to exercise for 30 minutes per day as per their health care provider.

Study Timeline

• Study Start: 2012-01
• Primary Completion: 2013-12
• Study Completion: 2013-12
• Study First Submitted: 2016-01-07
• Status Verified: 2016-05
• Study First Submitted QC: 2016-05-23
• Last Update Submitted: 2016-05-23
• Study First Posted: 2016-05-26
• Last Update Posted: 2016-05-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 84

Inclusion Criteria

• Post-MI hospital discharge within 2 weeks
• Enrolled in cardiac rehabilitation
• Prescribed anti-platelets, beta-blockers, ACE-inhibitors or ARBs, and/or statins on 1x/day regimen (for medication adherence trial)
• Prescribed exercise regimen (for exercise trial)
• Ability to read and write English
• Possession of a cell phone with text messaging capability

Exclusion Criteria

• Age < 18
• Incarcerated individuals
• Unable to read and write English
• Not in possession of a cell phone
• Patients prescribed medication regimen > 1x/day

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Medication text message	Text message reminder for medication adherence	Once daily text message reminder.
Exercise text message	Text message reminder for exercise regimen	4x daily text message reminder.

Primary Outcome Measures

Name	Time	Method
Medication adherence	12 months	Average medication adherence over 12 months after randomization, assessed with self-reported logs
Exercise frequency	12 months	Average frequency of exercise over 12 months after randomization, assessed with self-reported logs

Secondary Outcome Measures

Name	Time	Method
Exercise duration	12 months	Average duration of exercise assessed by BRUCE protocol
Full medication adherence	12 months	Average medication adherence over 12 months greater than .80