Repetitive transcranial stimulation (rTMS) in Treatment resistant obsessive compulsive disorder

Not yet recruiting

• Conditions: Mixed obsessional thoughts and acts,

• Registration Number: CTRI/2023/01/048707
• Lead Sponsor: Dr Kartikeya R Singh

Brief Summary

Repetitive transcranial magnetic stimulation  is FDA approved treatment for Obsessive compulsive disorder. As the disorder causes significant distress and dysfunction study has not been done for resistant cases of OCD wich account for 30 % of total cases.This creates a gap in the management of resistant cases of OCD.

Our study is aimed at adjunctive  treatment of resistant cases of OCD where the medications will not be changed during course of  therapy and results will be analysed subsequently.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-12-23
• Study Start: 2023-01-20

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 28

Inclusion Criteria

• Patients of either sex aged between 18 to 60 years.
• Diagnosed cases of treatment resistant Obsessive compulsive disorder.
• Normotensive patients.
• Age range:- 18- 60 years Patients who gave written informed consent.

Exclusion Criteria

• Patients unwilling to participate in the study or dropped out during study period.
• Current neurological or any comorbid psychiatric disorder.
• History of epilepsy, significant head injury, drug abuse or any neurosurgical procedure, hypertension.
• Subjects positive for TMS Adult Safety Screen (TASS) including individuals with cardiac pacemaker or metal in head.
• Subjects who received ECT (Electro Convulsive Therapy) or antipsychotics in past 6 months.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess the efficacy of rTMS (Repetitive transcranial magnetic stimulation) as an adjunctive treatment modality in patients of treatment resistant OCD (Obsessive Compulsive Disorder	Baseline and 2 weeks

Secondary Outcome Measures

Name	Time	Method
To compare the efficacy of active low frequency rTMS as an adjunctive treatment with the sham rTMS in cases of treatment resistant OCD	To compare the efficacy of active low frequency rTMS as an adjunctive treatment with the sham rTMS in cases of treatment resistant OCD after 2 weeks

Trial Locations

Locations (1)

1. Command hospital; 🇮🇳 Kolkata, WEST BENGAL, India

1. Command hospital

🇮🇳Kolkata, WEST BENGAL, India

Col Dr VS Chauhan

Principal investigator

9971224694

vinaychauhan2@gmail.com