tACS Brain Neuromodulation for Sensory and Motor Recovery After Neurological Impairments
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Neuropathic Pain Management
- Sponsor
- The University of Texas Health Science Center, Houston
- Enrollment
- 14
- Locations
- 1
- Primary Endpoint
- Heart rate variability (HRV) measurement
- Status
- Not Yet Recruiting
- Last Updated
- last year
Overview
Brief Summary
The overall goal is to investigate the effectiveness of a novel intervention - transcranial alternating current stimulation (tACS) for neuropathic pain management in people after spinal cord injury.
Investigators
Sheng Li
Professor
The University of Texas Health Science Center, Houston
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Heart rate variability (HRV) measurement
Time Frame: Change of HRV 10-15 minutes before and after the tACS intervention will be measured.
Heart rate variability (HRV) is the fluctuation in the time intervals between adjacent heartbeats (1). HRV indexes neurocardiac function and is generated by heart-brain interactions and dynamic non-linear autonomic nervous system (ANS) processes. HRV will be used as a surrogate assessment for autonomic nerve system
Pain scale (visual analogue scale, VAS) measurement
Time Frame: Change of VAS 5 minutes before and after the tACS intervention will be measured.
The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between "no pain" and "worst pain."