Physical activity and quality of life in people with multiple sclerosis in Tyrol, Austria

Not Applicable

• Conditions: Observation of the activity behaviour and quality of life in people with multiple sclerosis in Tyrol; Nervous System Diseases

• Registration Number: ISRCTN45742963
• Lead Sponsor: Karl Landsteiner Institute for Interdisciplinary Research at the Rehabilitation Center Muenster

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-01-27
• Last Update Posted: 15 July 2024
• Study Completion: 2026-06-30

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 550

Inclusion Criteria

1. Diagnosed with multiple sclerosis according to revised McDonald criteria (Thompson et al., 2018), independent of disease phenotype or ethnicity
2. Age =18 years
3. Principal residence in Tyrol
4. Excellent knowledge of the German language
5. EDSS-Score from 0 to 9.0 (Kurtzke 1983)

Exclusion Criteria

1. Recent relapse from MS (within 90 days prior to the study start)
2. Pregnancy
3. Comorbidity (malignant disease, dementia, other neurological or psychiatric diseases)

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Physical Activity measured by the International Physical Activity Questionnaire (IPAQ), Godin Leisure Time Exercise Questionnaire (GLTEQ) at baseline<br>2. Physical Activity measured by the Physical Activity Recall Assessment for People with Spinal Cord Injury (PARA-SCI) over 3 days<br>3. Physical Activity measured by the Actigraph GT3X-BT (ActiGraph) for 7 days<br>4. Health-related quality of life is measured by the Multiple Sclerosis International Quality of Life questionnaire (MusiQol) at baseline <br>5. Disease-specific factors are collected from the patient records at baseline

Secondary Outcome Measures

Name	Time	Method
1. Fatigue is measured by the Würzburger Erschöpfungsinventar (WEIMUS) at baseline<br>2. Depression is measured by the Hospital Anxiety and Depression Scale (HADS-D) at baseline<br>3. Self-efficacy is measured by the Unidimensional Self-Efficacy Scale for MS (USE-MS-G) at baseline<br>4. Mobility is measured by the Multiple Sclerosis Walking Scale-12 (MSWS-12) at baseline