Research on Optimization of treatment and brain function of acupuncture therapy for patients with panic disorder

Conditions

Trial Snapshot

No summary available.

•For patients:
•1. Patients with panic disorder who meet the diagnostic criteria for panic disorder (M.I.N.I diagnosis) of the American Mental Disorders Diagnosis and Statistics Manual(DSM)-Fourth edition;
•2. Aged 18-60 years;
•3. PDSS total score is more than 7 and HAMD- 17 total score is less than 18;
•4. Education above Junior middle school level;
•5. Sign the informed consent;
•6. Right-handed.
•For healthy controls:
•1. Aged 18 to 60 years, right-handed, junior high school education or above;
•2. Match with PD patient group in terms of gender, age, dexterity and education;
•3. PDSS total score is less than 6 and HAMD- 17 total score is less than 7;
•4. Signed the informed consent.

•For patient:
•1. According to the judgment of the researcher, the patient is at risk of self-injury, suicide or injury to others, or is at moderate risk of suicide as assessed by the MINI diagnosis;
•2. Patients with organic brain diseases, major physical diseases and infectious diseases;
•3. Consistent with the diagnosis of schizophrenia, bipolar disorder, depression, other anxiety disorders and other mental disorders;
•4. Evidence of drug dependence and psychoactive substance use;
•5. Patients who took SSRIs within 4 weeks before enrollment or received treatment with systemic effects on brain function;
•6. Pregnant and lactating women;
•7. Allergic to alcohol skin disinfection;
•8. Fear of acupuncture and acupuncture, needle fainting patients;
•9. Other conditions that the researcher considers inappropriate for inclusion;
•(Add the following exclusion criteria in patients with resting state MRI:Patients with metal implants and metal dentures in the body and MRI taboos such as claustrophobia.)
•For healthy controls:
•1. Those who have metal implants and metal dentures in their bodies, are pregnant or breastfeeding, and have MRI contraindications such as claustrophobia;
•2. No serious physical disease;
•3. No history of mental illness that meets the diagnostic criteria, no family history of mental illness;
•4. Those who have received systematic treatment that affects brain function within 4 weeks before enrollment.

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