Research on Optimization of treatment and brain function of acupuncture therapy for patients with panic disorder

Not Applicable

Recruiting

• Conditions: Panic Disorder

• Registration Number: ITMCTR2000004161
• Lead Sponsor: Beijing Anding Hospital, Capital Medical University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Male
• Target Recruitment: Not specified

Inclusion Criteria

For patients:
1. Patients with panic disorder who meet the diagnostic criteria for panic disorder (M.I.N.I diagnosis) of the American Mental Disorders Diagnosis and Statistics Manual(DSM)-Fourth edition;
2. Aged 18-60 years;
3. PDSS total score is more than 7 and HAMD- 17 total score is less than 18;
4. Education above Junior middle school level;
5. Sign the informed consent;
6. Right-handed.
For healthy controls:
1. Aged 18 to 60 years, right-handed, junior high school education or above;
2. Match with PD patient group in terms of gender, age, dexterity and education;
3. PDSS total score is less than 6 and HAMD- 17 total score is less than 7;
4. Signed the informed consent.

Exclusion Criteria

For patient:
1. According to the judgment of the researcher, the patient is at risk of self-injury, suicide or injury to others, or is at moderate risk of suicide as assessed by the MINI diagnosis;
2. Patients with organic brain diseases, major physical diseases and infectious diseases;
3. Consistent with the diagnosis of schizophrenia, bipolar disorder, depression, other anxiety disorders and other mental disorders;
4. Evidence of drug dependence and psychoactive substance use;
5. Patients who took SSRIs within 4 weeks before enrollment or received treatment with systemic effects on brain function;
6. Pregnant and lactating women;
7. Allergic to alcohol skin disinfection;
8. Fear of acupuncture and acupuncture, needle fainting patients;
9. Other conditions that the researcher considers inappropriate for inclusion;
(Add the following exclusion criteria in patients with resting state MRI:Patients with metal implants and metal dentures in the body and MRI taboos such as claustrophobia.)
For healthy controls:
1. Those who have metal implants and metal dentures in their bodies, are pregnant or breastfeeding, and have MRI contraindications such as claustrophobia;
2. No serious physical disease;
3. No history of mental illness that meets the diagnostic criteria, no family history of mental illness;
4. Those who have received systematic treatment that affects brain function within 4 weeks before enrollment.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
PDSS;

Secondary Outcome Measures

Name	Time	Method
HAMD;Chinese Traditional medicineSyndrome Observation Scale;PDQ-4+;PASS;