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临床试验/CTRI/2025/12/098718
CTRI/2025/12/098718尚未招募不适用

Evaluation of Hepatic Vasculature by Transesophageal Echocardiography (TEE) in Patients Undergoing Living Donor Liver Transplantation: A Prospective Observational Study

Institute of Liver and Biliary Sciences1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年12月22日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
30
试验地点
1

研究概览

简要总结

Liver Transplantation is a major surgery associated with severe haemodynamic changes.   Transesophageal Echocardiography (TEE) helps in real-time evaluation of hemodynamics of the patient and can play a vital role in management of such patients. As of now, TEE has primarily been used for evaluation of cardiac structures and hemodynamics in patients undergoing liver transplantation. However, with the advancement of technology, the role of TEE has expanded beyond the cardiac evaluation of the patients. There are also some reports about the utility of TEE for portal vein and hepatic vein evaluation in patients undergoing liver transplantation.   Immediate evaluation of portal vein and hepatic vein after graft reperfusion is of utmost importance for the early detection and correction of vascular complications. Currently, an in-field intraoperative doppler sonography of the hepatic vasculature is a standard practice. But this practice has some limitations, like the requirement of a radiologist present in the OR, and interference with the surgical field and a possible breach in sterility. On the other hand, TEE can provide an immediate, quick and repeated assessment of hepatic vasculature without risking any breach in field sterility.   As per our literature search, assessment of hepatic vasculature after graft reperfusion using TEE is limited. Hence, this study aims to evaluate portal vein, hepatic vein and hepatic artery using TEE during liver transplantation.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • Patents undergoing living donor liver transplantation.

排除标准

  • Patients having contraindications to TEE placement: High risk esophageal varices, Esophageal varices grade more than 2, History of recent upper abdominal bleed within 1 month, History of recent variceal ligation within 1 month, Gastric antral variceal ectasia, Gastric polyp, Coagulopathy, Esophageal strictures, Esophageal tumor, and Esophageal diverticula, History of esophageal surgery, Esophagitis.

研究者

申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Abhishek Arya

Institute of Liver and Biliary Sciences

研究点 (1)

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