oninvasive Evaluation of Hepatic Hemodynamics Using Xe Computed Tomography
Not Applicable
Recruiting
- Conditions
- iver disease (acute hepatitis, Chronic hepatitis, liver cirrhosis, hepatic failure, etc) Liver tumor (hepatocellular carcinoma, cholangiocellular carcinoma, metastatic liver tumor, etc)
- Registration Number
- JPRN-UMIN000008078
- Lead Sponsor
- St. Marianna University, School of Medicine, Department of Internal Medicine, Division of Gastroenterology & Hepatology
- Brief Summary
Takahashi H, Shigefuku R et al J Gastroenterol 2013 Takahashi H, Shigefuku R et al World J Gastroenterol 2014 Shigefuku R Takahashi H, et al Int J Mol Sci 2014 Shigefuku R Takahashi H, et al Int J Mol Sci 2016 Shigefuku R Takahashi H, et al BMC Gastroetenrol 2022
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 1000
Inclusion Criteria
Not provided
Exclusion Criteria
1. severe cardiac, renal and lung disease 2. consciouness distubance 3. severe allergy and asthma 4. pregnacy 5. Otherwise, in case that investigators judge the patient who is inappropriate for this study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. correlation between tissue blood flow and stage of fibrosis. 2. correlation between tissue blood flow and grade of Child-Pugh. 3. correlation between Xe solubility coefficient and stage of steatosis. 4. Alteration of tissue blood flow and Xe solubility coefficient before and after treatment (interferon, endoscopic procedure, operation, diet-exercise therapy, etc)
- Secondary Outcome Measures
Name Time Method 1. reproducibility 2. safety