An Observational study comparing the efficacy of low dose ketamine and paracetamol pretreatment in alleviating pain due to propofol injection.
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 300
- Locations
- 1
- Primary Endpoint
- to observe for pain reduction immediately after administration of 1/3rd dose of propofol then 1 min and 2 min
Study Overview
Brief Summary
Propofol short acting intravenous anaesthetic agent is extensively used because of its smooth induction and recovery .Its a agent of choice in day care anaesthesia ,for sedation in ICU,as maintenance agent in anaesthesia.However pain due to this is major drawback.Various strategies have been practiced to reduce pain like choosing a larger vein,cooling propofol,dilution of propofol,increasing speed of injection.
Ketamine and paracetamol are good analgesic properties so in this study comparing between two which provides better pain relief.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18.00 Year(s) to 65.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •American Society of Anesthesiologists physical status (ASAPS) I and II patients undergoing elective surgeries under general anaesthesia.
Exclusion Criteria
- •Suspected allergy to propofol,ASAPS 3 and 4,patient refusal,emergency surgeries.
Outcomes
Primary Outcomes
to observe for pain reduction immediately after administration of 1/3rd dose of propofol then 1 min and 2 min
Time Frame: to observe for pain reduction immediately after administration of 1/3rd dose of propofol then 1 min and 2 min
Secondary Outcomes
- to observe for hemodynamic changes if any before administering drug ,after intubation ,5 mins after intubation ,10 mins after intubation(0,5,10 mins)