Assessment of pain during drug injection when the drug is warm and cold in comparison with warm and cold intravenous fluid
- Conditions
- Factors influencing health status and contact with health services,
- Registration Number
- CTRI/2019/12/022468
- Lead Sponsor
- MS Ramaiah Medical College and hospitals
- Brief Summary
Propofol is the most commonly used rapidly acting intravenous agent forinduction of general anesthesia. However, pain during induction remains acommon problem, with many patients complaining pain was intense. Some patientseven reported to be having stated that the pain was most unbearable experienceduring the perioperative period. Pain may also reduce patientsatisfaction with anaesthesia. Different methods have been used to reduce this discomfort including,topical cooling with addition of lignocaine, combination of nitroglycerine and lignocaine with venous occlusion, local warming and local cooling, intravenous lignocaine injection priorto propofol injection and warming propofol to 37°C. Propofolinjection pain still remains a major problem because its complete eliminationis challenging. There are no studies on effect of warming of propofol and carrier fluidsto alleviate the pain on propofol injection. This paucity of literature in acommon clinical scenario has necessitated taking up this clinical study andthereby contributing to literature in this subject area under study. This study aims to determine the incidence of pain on injection ofpropofol and the degree of pain alleviation with propofol and carrier fluid atdifferent temperature.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 144
patients undergoing elective surgeries under general anaesthesia.
Allergy to propofol Inability to comprehend Verbal Rating Scale (VRS) Pregnant and breastfeeding women Peripheral neuropathy Patients with skin disease or erythema.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the incidence and degree of pain during Propofol injection using warm or cold propofol with heated or cold carrier fluid. immediately after intervention
- Secondary Outcome Measures
Name Time Method To observe hemodynamic changes during propofol injection at different temperatures. baseline, pre-induction, immediately after intervention, every minute for three minutes
Trial Locations
- Locations (1)
MS Ramaiah Medical College and hospitals
🇮🇳Bangalore, KARNATAKA, India
MS Ramaiah Medical College and hospitals🇮🇳Bangalore, KARNATAKA, IndiaRASHEEDA FAYAZIPrincipal investigator7358540270rasheedafayaz@gmail.com