A comparative study on the effect of carrier fluid and propofol temperature on reducing propofol injection pain

Propofol is the most commonly used rapidly acting intravenous agent forinduction of general anesthesia. However, pain during induction remains acommon problem, with many patients complaining pain was intense. Some patientseven reported to be having stated that the pain was most unbearable experienceduring the perioperative period. Pain may also reduce patientsatisfaction with anaesthesia. Different methods have been used to reduce this discomfort including,topical cooling with addition of lignocaine, combination of nitroglycerine and lignocaine with venous occlusion, local  warming and local  cooling, intravenous lignocaine injection priorto propofol injection and warming propofol to 37°C. Propofolinjection pain still remains a major problem because its complete eliminationis challenging. There are no studies on effect of warming of propofol and carrier fluidsto alleviate the pain on propofol injection. This paucity of literature in acommon clinical scenario has necessitated taking up this clinical study andthereby contributing to literature in this subject area under study. This study aims to determine the incidence of pain on injection ofpropofol and the degree of pain alleviation with propofol and carrier fluid atdifferent temperature.