Investigating dopamine synthesis capacity in (pathological) gamblers: An explorative Positron Emission Tomography study - Dopamine synthesis capacity and gambling

Radboud Universiteit Nijmegen0 个研究点目标入组 48 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

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•- Males volunteers between 18 and 65 years of age
•- Predominant right-handedness
•- Gambling status:
•- Gambling group: *pathological* or *problem* gamblers, as assessed by a score >= 4 on the SOGS questionnaire and the presence of 4 or more DSM-IV criteria for the diagnosis of pathological gambling (assessed using DIS-T)
•- Control group: score <= 2 on SOGS questionnaire and none of DSM-IV criteria for pathological gambling

•- Current psychiatric treatment (excluding cognitive behavioural therapy)
•- Major depressive disorder, post-traumatic stress disorder and substance/alcohol abuse/dependence (except nicotine dependence) in the 6 months prior to the start of the study
•- Lifetime history of other DSM-IV axis I disorders and related psychiatric treatment
•- Average use of more than 4 alcoholic beverages daily.
•- Self-reported inability or unease to cease smoking during the whole testing session
•- Use of psychotropic medication, or of recreational drugs over a period of 1 week prior to each test session, and use of alcohol within the last 24 hours before each measurement.
•- (History of) neurological treatment
•- (History of) epilepsy

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