NCT02248987已完成不适用
Study on Abnormal Dopamine Synthesis and Connectivity According to the Antipsychotic Treatment Response in Schizophrenia
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Striatal [18F]-DOPA uptake measured using positron emission tomographic 18F-dopa imaging.
研究概览
简要总结
The purpose of this study is to evaluate abnormal dopamine synthesis and connectivity according to the antipsychotic treatment response in schizophrenia.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 20 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •diagnosis of schizophrenia
- •clinically stable state
排除标准
- •history of previous head injury, epileptic disorder, other medical comorbidity
- •substance abuse/dependence
结局指标
主要结局
Striatal [18F]-DOPA uptake measured using positron emission tomographic 18F-dopa imaging.
时间窗: within 2 weeks from enrollment
次要结局
- resting state functional magnetic resonance imaging(within 2 weeks from enrollment)
- neurocognitive function test(within 2 weeks from enrollment)
- clinical measure including Positive and Negative Syndrome Scale(within 2 weeks from enrollment)
- diffusion tensor imaging(within 2 weeks from enrollment)
研究者
Jun Soo Kwon
professor
Seoul National University Hospital
研究点 (1)
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