Mechanisms of Fronto-Subcortical Dysfunction: Comparing PD and OCD

• Conditions: Parkinson's Disease; Obsessive-Compulsive Disorder

• Registration Number: NCT00790634
• Lead Sponsor: Sheba Medical Center

Brief Summary

The purpose of this study is to characterize and compare irregularities in dopaminergic function in fronto-subcortical circuits, between Parkinson's Disease patients (ON and OFF medication) and patients with obsessive-compulsive disorder, by examining performance on cognitive tasks involving cognitive flexibility, decision-making, and attentional bias.

Detailed Description

Not available

Study Timeline

• Status Verified: 2008-11
• Study First Submitted: 2008-11-12
• Study First Submitted QC: 2008-11-12
• Last Update Submitted: 2008-11-12
• Study First Posted: 2008-11-13
• Last Update Posted: 2008-11-13
• Study Start: 2008-12
• Primary Completion: 2011-12
• Study Completion: 2011-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• idiopathic PD or
• OCD
• for control group - age-matched to study groups

Exclusion Criteria

• psychotic symptoms (past or present)
• head injury with loss of consciousness
• other neurological conditions (excepting PD in PD group)
• for OCD group - use of dopaminergic medications

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified