Enhanced Recovery After Surgery Versus Conventional Approach in Peptic Perforation-A Randomized Control Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Length of hospital stay
研究概览
简要总结
This study compares 2 different ways of perioperative management in patients of peptic perforation. Experimental arm is the ERAS arm( Enhanced recovery after surgery) and the comparative arm is Conventional arm.
详细描述
While the conventional approach to perioperative management can potentially prolong the post operative hospital stay, ERAS(Enhanced recovery after surgery), a multi-modal and multispeciality approach to perioperative management may reduce the length of hospital stay. In the preoperative period, patients will be counselled regarding the operative procedure and particulars of the perioperative management.In the intra-operative period short acting general anesthetic agents and short acting muscle relaxants will be used.Intravenous fluid administration will be goal directed. After the operative procedure, bilateral rectus sheath block will be administered. Patient will also receive post-operative nausea and vomiting prophylaxis. Nasogastric tube will be removed immediately after the operative procedure. In the post operative period, patients will be encouraged to ambulate early. Enteral nutrition will be initiated as early as possible. Indwelling catheters will be removed in the early post-operative procedure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patient diagnosed with peptic perforation intra -operatively
- •Perforation of size <=1 cm
- •Patient age more than 18 years
- •American Society of Anesthesiologists score of I or II
排除标准
- •Refractory septic shock at presentation.
- •Known Chronic kidney disease/ Chronic liver disease patients
- •Pregnant patients.
- •Patients with history of chronic steroid abuse.
- •Intraoperatively
- •Patient with coexistent peptic perforation with bleeding ulcer.
- •Peptic perforation requiring procedure other than Omental patch repair.
- •Sealed perforations.
- •Malignant perforation.
- •Patient requiring Positive Pressure Ventilator support post operatively for more than 12 hours.
- •Patient requiring urinary catheterization for other indications.
- •Coexistent neurological or psychiatric illness or unable to understand the study.
- •Patient refusing for consent.
结局指标
主要结局
Length of hospital stay
时间窗: Post operative period up-to one month.
Duration from the time of operation to time of discharge
次要结局
- Recovery of functional parameters(Post operative period up-to one month.)
- Post operative complications(Post operative period up-to three months.)
研究者
Tushar Subhadarshan Mishra
Additional Professor
All India Institute of Medical Sciences, Bhubaneswar