Booster Dose of HCG for Unruptured Follicle in Non IVF/ICSI Cycles
- Conditions
- LUF - Luteinised Unruptured Follicle Syndrome
- Interventions
- Drug: Saline Solution
- Registration Number
- NCT03580031
- Lead Sponsor
- Tanta University
- Brief Summary
This study will be conducted to assess the effect of booster dose of hCG on the unruptured follicles in non IVF/ICSI cycles.
- Detailed Description
In this study enrolled patients (n=160) who underwent controlled ovarian stimulation and timed intercourse with unruptured mature graffian follicle 48 hours after IM 10,000 IU HCG dose. Patients were allocated randomly into intervention group and control group. In the intervention group another booster dose (10,000 IU of hCG) was given IM while in the control group 2 ml normal saline was given IM leaving follicles for spontaneous rupture
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 110
- Ordinary stimulated cycles
- IUI stimulated cycles
- Unruptured follicle after 10000 IU IM HCG triggering
- IVF/ICSI cycles
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Control group Saline Solution Saline 2m Injection im 48 hours after the first triggering dose Study group hCG HCG IM 10,000 IU Im 48 hours after first triggering dose
- Primary Outcome Measures
Name Time Method Ovulation rate 48 hours rupture of dominant follicle manifested by disappearance of follicle and presence of free fluid in douglas pouch
- Secondary Outcome Measures
Name Time Method Pregnancy rate 15 days Number of cases with positive serum pregnancy test
Trial Locations
- Locations (1)
Ayman Shehata Dawood
🇪🇬Tanta, Algharbia, Egypt