Adaptive Treatment for Adolescent Cannabis Use Disorders

Not Applicable

Completed

• Conditions: Addictive Behaviors; Cannabis Use Disorder; Mental Disorders
• Interventions: Behavioral: ACRA; Behavioral: CBT

• Registration Number: NCT01656707
• Lead Sponsor: UConn Health

Brief Summary

The purpose of this study is to examine an Adaptive Treatment approach in order to improve outcomes of youth with Cannabis Use Disorders who are poor responders to treatment.

Detailed Description

The study will address the current contrasts in youth response to treatment, the problem of poor response to treatment and the prevention of relapse. Results from the study may support Adaptive Treatment as an efficacious approach for youth with Cannabis Use Disorder who are poor responders to treatment.

Poor responders fall into two categories, those who failed to achieve a negative drug urinalysis during the last session of the initial MET/CBT-7 treatment they attended, and those who either dropped out or were administratively discharged at any time during the initial MET/CBT-7 treatment.

Study Timeline

• Study Start: 2011-09
• Study First Submitted: 2012-08-01
• Study First Submitted QC: 2012-08-01
• Study First Posted: 2012-08-03
• Primary Completion: 2016-07
• Study Completion: 2016-07
• Status Verified: 2017-04
• Last Update Submitted: 2017-04-10
• Last Update Posted: 2017-04-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 172

Inclusion Criteria

• 13-18 years of age at the time of intake assessment
• Current diagnosis of DSM-IV Cannabis Abuse or Dependence
• Able to read and comprehend English at a 5th grade level
• Residence within 45 minutes drive from the UCHC Farmington treatment site
• Participant and a parent/legal guardian responsible for providing collateral information agree to sign an IRB approved consent form
• Participant and a parent/legal guardian responsible for providing collateral information agree to provide locator information
• The family is not planning to move from the area during the next six months

Exclusion Criteria

• Meet criteria for dependence of any other substance of abuse other than nicotine or alcohol
• Report suicidal ideation with a plan, suicidal behavior, a plan to hurt oneself or other, or a history of self-injurious behavior all occurring in the last 30 days
• Meet a lifetime diagnosis of schizophrenia
• Has any current health (i.e. medical, psychiatric) condition that will compromise the participant's ability to regularly attend treatment
• Demonstrate an inability or unwillingness to provide locator information

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
ACRA	ACRA	Ten weekly 60-minute sessions of Adolescent Community Reinforcement Approach (ACRA) will be provided as an Adaptive treatment condition.
Cognitive Behavioral Therapy (CBT)	CBT	Ten weekly, 60-minute sessions of augmented individualized Cognitive Behavioral Therapy (CBT)will be provided as an Adaptive Treatment condition

Primary Outcome Measures

Name	Time	Method
1.) To evaluate the efficacy of AT for youth who have been defined as poor responders to an evidence-based practice intervention such as the initial MET/CBT-7.	one year	Each participant will serve as his/her own control. The outcomes will include the T-ASI, T-ASI-P, and drug urinalyses.

Secondary Outcome Measures

Name	Time	Method
To assess outcomes as a function of mediator variables such as self-efficacy, coping skills, readiness to change, and environmental support (i.e., family and peer), within each of the AT interventions.	one year	The secondary outcome measures will include the SCQ, CRI, PRQ, and SSQ.

Trial Locations

Locations (1)

University of Connecticut Health Center; 🇺🇸 Farmington, Connecticut, United States