Determination of central pain modulation biomarkers to characterize and profile cancer patients with refractory pain

niversity of Santiago de Compostela0 个研究点目标入组 750 人开始时间: 2023年5月30日最近更新: 2024年1月8日

试验速览

暂无简介。

•Cancer patients with pain:
•1. Adult subjects = 18 years old
•2. Able to provide informed consent to participate in the study
•3. Able to self-report pain
•4. To have a diagnosis of cancer affecting the lung, breast, pancreas or colon (with metastases or not)
•5. The life expectancy of at least six months
•6. Cancer pain persisting despite best-tolerated pharmacological treatment
•7. Pain rated =5 on a 0-10 Numeric Rating Scales (NRS) persisting for over 1 month prior to enrolment
•8. Ability to use the internet and WhatsApp or have a person (relative, caregiver) to help them
•Cancer patients with no pain:
•1. Adult subjects = 18 years old
•2. Able to provide informed consent to participate in the study
•3. Able to self-report pain
•4. To have a diagnosis of cancer affecting the lung, breast, pancreas or colon (with metastases or not)
•5. The life expectancy of at least six months
•6. No chronic pain after cancer disease or treatment
•7. Ability to use the internet and WhatsApp or have a person (relative, caregiver) to help them

•Cancer patients with pain:
•1. Pregnant women or women of fertile age that did not have efficacious contraception during the whole period of the study
•2. Neurological or psychiatric diseases (except anxiety or depression)
•3. Unstable medical conditions (e.g., uncontrolled diabetes, uncompensated cardiac issues, heart failure or chronic obstructive pulmonary disease)
•4. History of neurosurgery, traumatic brain injury with loss of consciousness, and/or cortical lesions
•5. Present risk factors for receiving tES (e.g., history of epilepsy, metal devices in the brain, etc.)
•6. History of non-malignant chronic pain
•Cancer patients with no pain:
•1. Pregnant women or women of fertile age that did not have efficacious contraception during the entire period of the study.
•2. Neurological or psychiatric diseases (except anxiety or depression).
•3. Unstable medical conditions (e.g., uncontrolled diabetes, uncompensated cardiac issues, heart failure or chronic obstructive pulmonary disease).
•4. History of neurosurgery, traumatic brain injury with loss of consciousness, and/or cortical lesions.
•5. History of non-malignant chronic pain.

发起方

niversity of Santiago de Compostela