DRKS00031070
招募中
3 期
Determination of central pain modulation biomarkers to characterize and profile cancer patients with refractory pain and adaptation and validation of a home-based transcranial brain stimulation procedure for their palliative care - PAINLESS-TreatCANCERPAI
niversitätsmedizin Göttingen0 个研究点目标入组 450 人2023年1月31日
概览
- 阶段
- 3 期
- 干预措施
- 未指定
- 疾病 / 适应症
- C00-C97
- 发起方
- niversitätsmedizin Göttingen
- 入组人数
- 450
- 状态
- 招募中
- 最后更新
- 去年
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •Adult subjects \= 18 years old.
- •\-Able to provide informed consent to participate in the study.
- •\-Able to self\-report pain.
- •\-To have a diagnosis of cancer affecting lung, breast, pancreas or colon (with metastases or not).
- •\-The life expectancy of at least six months.
- •\-Cancer pain persisting despite best tolerated pharmacological treatment
- •\-Pain rated \>\= 5 on a 0\-10 Numeric Rating Scale (NRS) persisting for over 1 month prior to enrolment.
- •\-Ability to use internet and WhatsApp or have a person (relative, caregiver) to help them.
排除标准
- •\-Pregnant women or women of fertile age that did not have efficacious contraception during the whole period of the study.
- •\-Neurological or psychiatric diseases (except anxiety or depression)
- •\-Unstable medical conditions (e.g., uncontrolled diabetes, uncompensated cardiac issues, heart failure or chronic obstructive pulmonary disease).
- •\-History of neurosurgery, traumatic brain injury with loss of consciousness, and/or cortical lesions
- •\-Present risk factors for receiving tES (e.g., history of epilepsy, metal devices in the brain, etc.).
- •\-History of non\-malignant chronic pain.
结局指标
主要结局
未指定
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