NCT01006174已完成不适用
Dietary Lipids as Primary Modulators of Carotenoid Absorption in Vegetables
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 55
- 试验地点
- 2
- 主要终点
- Evaluating the impact of dietary lipid profiles on intestinal absorption of carotenoids from vegetables.
研究概览
简要总结
The purpose of this research study is to determine how dietary fats and oils influence the absorption of beneficial plant pigments (carotenoids) from vegetables. The study will examine changes in blood carotenoids in response to eating a salad with different fats/oils.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age range: 18-50 years.
- •Body mass index (BMI: weight (kg)/height (m2)) ranging from 20-29 kg/m²
- •Weight stable (<4.5 kg change within the last 3 months),
- •Constant habitual activity pattern, not to exceed activities of a recreational level over the past 3 months.
- •Must be pre-menopausal
- •Have clinically normal blood profiles (specifically normal liver and kidney functions and fasting blood glucose of ≤110 mg/dl)
- •Non-smoking
- •Non-diabetic
- •No current or planned pregnancy
- •Not using any hormone-based contraceptive, e.g., pill, patch, injection, implants, etc.
- •No current use of medication affecting lipid profile
- •No intestinal disorders including lipid malabsorption, lactose intolerance
- •No heavy consumption of alcohol (>2 drinks per day)
- •No current use of dietary supplements that affect cholesterol, (e.g. Benocol or fiber supplements) or a willingness to discontinue their use during the study.
排除标准
- •Menopausal
- •Currently pregnant
- •Currently using any type of hormone-based contraceptives, (e.g., pill, patch, injection, implants, etc.)
- •Use of lipid altering medications
结局指标
主要结局
Evaluating the impact of dietary lipid profiles on intestinal absorption of carotenoids from vegetables.
时间窗: 66 days
次要结局
未报告次要终点
研究者
Wayne Campbell
Wayne Campbell, Ph.D.
Purdue University
研究点 (2)
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