Adrenaline use in local infiltration analgesia during TKA;Randomized, double blind, controlled study

Phase 4

• Conditions: knee wear; osteoarthritis of the knee joint; 10023213

• Registration Number: NL-OMON40518
• Lead Sponsor: Orbis Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

• Painful and disabled knee joint resulting from osteoarthritis
• High need to obtain pain relief and improve function
• Able and willing to follow instructions
• Informed consent

Exclusion Criteria

• Active infection in knee
• General infection
• Distant foci of infections which may spread to the implant site
• Failure of previous joint replacement
• Pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>VAS-painscore, post operative pain relief<br /><br>- Direct after the operation<br /><br>- Before and after the first mobilisation<br /><br>- Pain measure 3 times a day on standard time 3 a day on fixed intervals until<br /><br>discharge</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Amount of post operative analgesia use direct post operative till day of<br /><br>discharge<br /><br>- Time to fisrt mobilisation<br /><br>- Length of hospital stay<br /><br>- Adverse events/complications: Intra-operative, post-operative during pilot<br /><br>study</p><br>