NL-OMON38406已完成不适用
Comparison of pre- and postoperative clinical target volumes at CT and MRI imaging in breast-conserving therapy: A prospective cohort study. - Clinical target volumes in breast-conserving therapy.
niversitair Medisch Centrum Utrecht0 个研究点目标入组 27 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 27
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99(—)
入选标准
- •- Female gender;
- •- Age >= 18 years,
- •- cT1-T2N0-1M0 breast cancer;
- •- Scheduled for breast-conserving therapy;
- •- Before breast-conserving surgery;
- •- Written informed consent.
排除标准
- •- Legal incapability;
- •- Insufficient command of the Dutch language;
- •- History of ipsilateral breast surgery (benign, malign, augmentation, reduction);
- •- Inability to maintain the standard supine RT treatment position for 30 minutes;
- •- Exclusion criteria for MRI following the protocol of the department of radiology UMCU;
- •- GFR of <45mL/min/1.73m2. In patients with known risk factors a minimum GFR of <60mL/min/1.73m2 will be required, according to the UMCU protocol;
- •- Iodine allergy (contraindication for iodine-based intravenous contrast agents);
- •- Treated with neo-adjuvant chemotherapy.
- •- Treated with modified radical mastectomy.
- •- Treated with en-block axillary lymph node dissection.
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