The effect of autologous bone marrow stem cells on knee osteoarthritis

Not Applicable

• Conditions: knee osteoarthritis.; Primary arthrosis of other joints

• Registration Number: IRCT2015050922174N1
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

patients with knee joint osteoarthritis referring to orthopedic and rehabilitation clinics, cell therapy center of Ghadir Mother and Child hospital, and hospitals affiliated to Shiraz University of Medical Sciences.
Exclusion criteria: very advanced or severe osteoarthritis; age over 65 years old; BMI greater than 25; inflammatory joint and rheumatic disease; history of cancer; chemotherapy or use of immunosuppressive drugs; diabetes; history of smoking; Knee joint laxity; varus and valgus deformity of the knee.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Activity level function. Timepoint: 3, 6, 12 month. Method of measurement: History.

Secondary Outcome Measures

Name	Time	Method
Swelling and morning stiffness. Timepoint: 3, 6, 12 month. Method of measurement: History and physical exam.;Severity and frequency of pain. Timepoint: 3, 6, 12 month. Method of measurement: History.;Knee locking and giving way. Timepoint: 3, 6, 12 month. Method of measurement: History.;Activity level before and after injection. Timepoint: 3, 6, 12 month. Method of measurement: History.