Phase IV Recruiting
试验速览
- 阶段
- 4 期
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- number of analgesic request
研究概览
简要总结
intraperitoneal nebulisation with magnesuim sulphate will reduce post operative pain and analgesic consumption in postoperative period following laparoscopic cholecystectomy.
详细描述
Sixty patients undergoing laparoscopic cholecystectomy belonging to American Society of Anaesthesiologist (I-II) of age 18-65 yrs will be enrolled.Group one (n=30) will receive 1.5 gm magnesium sulphate diluted in 3ml of normal saline and group 2 (n=30) will receive 5 ml of NS.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Magnesium sulphate
intraperitoneal nebulisation of 1.5 gm of magnesium sulphate with 2 ml of normal saline at the end of surgery before closure
干预措施: intraperitoneal nebulisation of magnesium sulphate (Drug)
normal saline
intraperitoneal nebulisation of 5 ml of normal saline after end of surgery before closure
干预措施: intraperitoneal nebulisation of magnesium sulphate (Drug)
结局指标
主要结局
number of analgesic request
时间窗: 24 hour
time to first analgesic request is taken as duration of effective analgesia number of analgesic request in first 24 hours were also counted
次要结局
- VAS score(first complaint of pain, 6 hrs, 12 hrs, 24 hrs)
- nausea and vomiting(24 hrs)
- respiratory rate(24 hrs)
- sedation(24hrs)
研究者
sujata niroula
junior resident
B.P. Koirala Institute of Health Sciences