Phase IV Recruiting
Overview
- Phase
- Phase 4
- Intervention
- intraperitoneal nebulisation of magnesium sulphate
- Conditions
- Postoperative Pain
- Sponsor
- B.P. Koirala Institute of Health Sciences
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- number of analgesic request
- Last Updated
- 14 years ago
Overview
Brief Summary
intraperitoneal nebulisation with magnesuim sulphate will reduce post operative pain and analgesic consumption in postoperative period following laparoscopic cholecystectomy.
Detailed Description
Sixty patients undergoing laparoscopic cholecystectomy belonging to American Society of Anaesthesiologist (I-II) of age 18-65 yrs will be enrolled.Group one (n=30) will receive 1.5 gm magnesium sulphate diluted in 3ml of normal saline and group 2 (n=30) will receive 5 ml of NS.
Investigators
sujata niroula
junior resident
B.P. Koirala Institute of Health Sciences
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Arms & Interventions
Magnesium sulphate
intraperitoneal nebulisation of 1.5 gm of magnesium sulphate with 2 ml of normal saline at the end of surgery before closure
Intervention: intraperitoneal nebulisation of magnesium sulphate
normal saline
intraperitoneal nebulisation of 5 ml of normal saline after end of surgery before closure
Intervention: intraperitoneal nebulisation of magnesium sulphate
Outcomes
Primary Outcomes
number of analgesic request
Time Frame: 24 hour
time to first analgesic request is taken as duration of effective analgesia number of analgesic request in first 24 hours were also counted
Secondary Outcomes
- VAS score(first complaint of pain, 6 hrs, 12 hrs, 24 hrs)
- nausea and vomiting(24 hrs)
- respiratory rate(24 hrs)
- sedation(24hrs)