Combining prebiotics or/and probiotics to improve the immunity of Children.
Completed
- Conditions
- Microbial composition of the GI-tract, Gut health, Gut integrity, Severity and Frequency of common infections and side effects (like e.g common cold, flue, fever, diarrhoea, Defecation patern, Earinfection, Behaviour, Sleeping patterns, etc.)
- Registration Number
- NL-OMON27904
- Lead Sponsor
- Frisian Flag (initiator/sponsor), Jakarata, Indonesia / BPPT, Jakarta, Indonesia / Soetomo Hospital, Surabaja, Indonesia / Friesland Foods, Leeuwarden (Sponsor/ initiator),The Netherlands
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 240
Inclusion Criteria
1. Healthy children
2. Age between 1-5 years
Exclusion Criteria
Children with:
1. Crohns, atopic disease.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Weekly questionaires are filled in by the caregivers (and in severe case:P diagnose by the specialist): <br /><br>1) the length of diarhoea <br /><br>2) the number of diarrhoea episodes <br /><br>3) severity of diarrhea<br /><br>4) the length of upper respiratory tract infections (UTRI) <br /><br>5) the number of UTRI <br /><br>6) severity of URTI. <br /><br><br /><br>Monthly data will be colected on: <br /><br>1) children growth-development status<br /><br><br /><br>Fecal samples are taken at time piont: 0 months, 1 months, 3 months and 6 months
- Secondary Outcome Measures
Name Time Method Weekly questionaires with:<br /><br>1) Behaviour of the child<br /><br>2) Allergy symptoms (eczema, hay fever, asthma etc.)<br /><br>3) Fever<br /><br>4) Day care attendance<br />