Analgesic efficacy of interpleural and paravertebral block

Not Applicable

Completed

• Conditions: Analgesia for mastectomy; Surgery

• Registration Number: ISRCTN13324055
• Lead Sponsor: The Newcastle upon Tyne Hospitals NHS Foundation Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-11-10
• Study Completion: 2016-01-01
• Last Update Posted: 26 February 2018

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 70

Inclusion Criteria

1. Female patients
2. Between the age of 18 and 85
3. Undergoing elective mastectomy at the RVI

Exclusion Criteria

1. Any procedure other than sentinel node biopsy in addition to simple mastectomy. This includes axillary node clearance and reconstructions.
2. BMI>35
3. Musculoskeletal deformity
4. Local infection at paravertebral or interpleural injection site
5. Coagulopathy
6. Respiratory disease which limits functional capacity
7. Neurological disease
8. Allergy or contraindication to local anaesthetics, opiates, paracetamol, parecoxib, volatile or intravenous anaesthetics and neuromuscular blockade.
9. Chronic pain treated by long term opiates
10. Psychiatric disease
11. Pregnancy or breast feeding
12. Patient refusal or incapacity
13. Anticipated difficult intubation which would preclude the use of neuromuscular blockade
14. Day case procedure planned

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
VAS pain score measured at six hourly intervals for the first 24 hours following mastectomy

Secondary Outcome Measures

Name	Time	Method
1. Nausea and vomiting rate<br>2. 24-hour morphine consumption