Efficacy of different doses of epidural dexamethasone with bupivacaine versus plain bupivacaine for post operative analgesia in patients undergoing abdominal and lower limb surgeries

Dr Santhosh M C B1 个研究点分布在 1 个国家目标入组 90 人开始时间: 2024年1月2日最近更新: 2024年9月1日

试验速览

阶段: 3 期
状态: 招募中
发起方
入组人数: 90
试验地点: 1
主要终点: To compare duration of post operative analgesia between two different doses of dexamethasone as adjuvant versus plain bupivacaine among patients undergoing abdominal and lower limb surgeries

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

In the study we are evaluating duration of post operative analgesia provided by epidural bupivacaine with either 4mg dexamethasone or 8mg dexamethasone in comparison to plain bupivacaine alone among patients undergoing abdominal and lower limb surgeries.

研究设计

研究类型: Interventional
分配方式: Computer generated randomization
盲法: Participant and Investigator Blinded

入排标准

年龄范围: 18.00 Year(s) 至 60.00 Year(s)（—）
性别: All

入选标准

•Patients of both sexes aged more than or equal to 18 years Patients undergoing abdominal and lower limb surgeries American society of anaesthesiologists grade I and II Patients who are willing to participate in the study with informed consent.

排除标准

•Anaphylaxis to the study drug dexamethasone and bupivacaine Patients with opioid drug intake for other co morbid conditions Patients on any other routine analgesics for other conditions Body mass index of more than or equal to 25kg/sq.m Patients who are known diabetics Any complications during insertion of epidural catheter Any intra operative or post operative complications.

结局指标

主要结局

To compare duration of post operative analgesia between two different doses of dexamethasone as adjuvant versus plain bupivacaine among patients undergoing abdominal and lower limb surgeries

时间窗: 24 hours

次要结局

To compare adverse events between the groups for 24 hours after giving epiduraL top-up(24 hours)

研究者

发起方

Dr Santhosh M C B

申办方类型

Other [self]

研究点 (1)

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