Study of 18F-FAPI Applied to Gastrointestinal Cancer

Not yet recruiting

• Conditions: Gastrointestinal Cancer
• Interventions: Diagnostic Test: 18F-FAPI and 18F-FDG PET/CT

• Registration Number: NCT05788874
• Lead Sponsor: First Affiliated Hospital Xi'an Jiaotong University

Brief Summary

Comparison of tumor volume, number, and SUVmax of different primary foci (gastric, duodenal, and colon cancer), lymph node metastases (neck and supraclavicular, mediastinal, abdominal, and pelvic), and distant metastases (brain, lung, liver, bone, pleura, and peritoneum) detected by 18F-FAPI versus 18F-FDG PET/CT imaging.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-03-16
• Study First Submitted QC: 2023-03-28
• Study First Posted: 2023-03-29
• Status Verified: 2023-04
• Last Update Submitted: 2023-04-12
• Last Update Posted: 2023-04-14
• Study Start: 2023-05
• Primary Completion: 2024-06
• Study Completion: 2024-12

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Patients with high clinical suspicion of gastrointestinal tumor and negative 18F-FDG at first diagnosis
• Post-treatment patients with high clinical suspicion of recurrence or metastasis and negative 18F-FDG

Exclusion Criteria

• The diagnosis can be clarified by 18F-FDG PET/CT examination
• The presence of recurrence or metastasis can be clarified by 18F-FDG PET/CT examination

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
18F-FAPI	18F-FAPI and 18F-FDG PET/CT	-
18F-FDG	18F-FAPI and 18F-FDG PET/CT	-

Primary Outcome Measures

Name	Time	Method
SUVmax	1 day (During the inspection)	Measurement of the maximum standardized uptake value of the lesion