Outcome of Local Versus General Anesthetic for Staged Carotid Endarterectomy Prior To CABG, Cohort Study
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 44
- Primary Endpoint
- Stroke
Study Overview
Brief Summary
A retrospective analysis of all patients that underwent carotid endarterectomy (CEA) for stenotic disease - diagnosed at pre-operative investigation - prior to CABG as staged operation within 6- months.
The rate of postoperative stroke and complications was compared between CEA performed under Local anaesthetic (LA) to those performed under General anaesthetic (GA).
Detailed Description
The primary outcome was the rate of postoperative stroke in patients that had staged CEA prior to CABG. This was defined as CEA within a period of 4 weeks prior to CABG.
We retrospectively looked at those patients that fulfilled the inclusion criteria and had CEA performed either under LA (Group A) or under GA (Group B). We measured the 30 days' postoperative stroke rate as the main outcome. We also looked at the rate of intraoperative stroke.
Additionally, we assessed the rate for developing nerve injuries and/or hematoma postoperatively. Finally, we examined the risk for developing postoperative stroke in patients with bilateral significant carotid artery disease that underwent surgery in one side.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •All patients that had carotid endarterectomy performed in staged fashion within 6 months before a CABG operation.
Exclusion Criteria
- •Patients diagnosed with symptomatic carotid disease
Outcomes
Primary Outcomes
Stroke
Time Frame: 30 days
a transient ischaemic attack (TIA), or a disabling stroke within 30 days of the carotid endarterectomy procedure.
Secondary Outcomes
- Major bleeding(30 days)
- Minor bleeding(30 days)
- Nerve injuries(30 days)
Investigators
Thomas Aherne
Site Investigator
National University of Ireland, Galway, Ireland