Effect of Propolis extract on non-alcoholic fatty liver disease

Phase 2

• Conditions: on- alcoholic fatty liver disease (NAFLD).; Fatty (change of) liver, not elsewhere classified; K76.0

• Registration Number: IRCT20180824040857N1
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 6 October 2020

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

Having evidence of fibrosis and steatosis on liver elastography
The absence of alcohol consumption
Having no secondary causes of hepatic steatosis such as hepatitis C virus, autoimmune hepatitis, haemochromatosis, hypopituitarism, hypothyroidism, Wilson’s disease, and regular use of hepatotoxic drugs (e.g., amiodarone, tamoxifen, valproate, methotrexate) or corticosteroids.

Exclusion Criteria

Pregnancy
Lactation
Having weight management program

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hepatic steatosis. Timepoint: At the beginning of the study and the fourth month of the intervention. Method of measurement: Two-dimensional shear wave elastography (2-D SWE).;Hepatic fibrosis. Timepoint: At the beginning of the study and the fourth month of the intervention. Method of measurement: Two-dimensional shear wave elastography (2-D SWE).