Bilateral Uterine Artery Ligation in Reducing Incidence of Postpartum Hemorrhage in Cesarean Section
Not Applicable
Completed
- Conditions
- Post Partum Hemorrhage
- Interventions
- Procedure: bilateral uterine artery ligation
- Registration Number
- NCT03591679
- Lead Sponsor
- Assiut University
- Brief Summary
The patients were recruited from women attending labor ward to undergo cesarean section.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 1070
Inclusion Criteria
- Women with one or more of the following conditions undergoing cesarean section for obstetric indication were included:
- Maternal anemia (not less than 7 gm %).
- Macrosomic baby >4kgs.
- Twin pregnancy and high order pregnancy.
- Polyhydramnios.
- Grand multipara.
- Previous history of atonic postpartum hemorrhage.
- Prolonged vaginal delivery.
- Emergency cesarean.
- Chorioamnionitis.
Exclusion Criteria
-
- Placenta previa.
- Patients with bleeding tendency (congenital or acquired)
- Ante-partum hemorrhage.
- Patients with no risk for uterine atony.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description study group Oxytocin patients at risk of uterine atony undergoing cesarean section underwent bilateral uterine artery ligation and received oxytocin. study group bilateral uterine artery ligation patients at risk of uterine atony undergoing cesarean section underwent bilateral uterine artery ligation and received oxytocin. control group Oxytocin patients at risk of uterine atony undergoing cesarean section received oxytocin only.
- Primary Outcome Measures
Name Time Method mean Blood loss after placental separation 30 minutes by using weight of soaked towels (weight of soaked towel - weight of dry towel) and amount of blood in suction set
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie uterine atony and how does bilateral uterine artery ligation affect these pathways?
How does bilateral uterine artery ligation compare to oxytocin in preventing postpartum hemorrhage during cesarean sections?
Are there specific biomarkers that identify patients most likely to benefit from uterine artery ligation for postpartum hemorrhage prevention?
What are the potential adverse events associated with bilateral uterine artery ligation and how can they be managed in high-risk patients?
What combination therapies involving uterine artery ligation and uterotonic agents are being explored for postpartum hemorrhage prevention?
Trial Locations
- Locations (1)
Ahmed Abbas
🇪🇬Assiut, Cairo, Egypt
Ahmed Abbas🇪🇬Assiut, Cairo, Egypt