Investigation of biomarkers of fatigue and mental health in employees' medical examinations.
Not Applicable
- Conditions
- Healthy adults
- Registration Number
- JPRN-UMIN000011068
- Lead Sponsor
- The Jikei University School of Medicine
- Brief Summary
In this study, we measured anti-human herpesvirus (HHV-) 6 antibody titers and salivary HHV-6 DNA quantities as a biomarker of fatigue. There was a significant decrease in the seropositivity of HHV-6 antibodies in subjects of 50 years and older, and age was significantly negatively correlated with anti-HHV-6 antibody titers. Age and salivary HHV-6 DNA quantities were also significantly negatively correlated.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 77
Inclusion Criteria
Not provided
Exclusion Criteria
Lack of ability to consent, severe physical illness, people judged not suitable by doctor.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular pathways link HHV-6 reactivation to chronic fatigue in aging populations?
How do HHV-6 antibody titers compare to other viral biomarkers in predicting workplace mental health decline?
Can salivary HHV-6 DNA quantification improve fatigue risk stratification in occupational health screening?
What adverse effects are associated with HHV-6-targeted interventions for fatigue management in middle-aged adults?
How does HHV-6 biomarker analysis complement cortisol or inflammatory markers in occupational stress assessment?