Effect of Phytochemicals From Theobroma Cacao on Mental Energy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 2
- 主要终点
- Correct Responses on Serial 7 Subtraction Task
研究概览
简要总结
The purpose of this study is to determine which substances in cocoa produces changes in mental energy. This is a double blind study. The primary outcome measures are performance on tasks of sustained attention (serial subtract, continuous performance test and Bakan task) at pre and 90, 120 and 160 minutes post intervention, energy and fatigue symptoms (profile of mood state), and ratings of motivation to perform cognitive tasks. The assigned interventions are the following:
详细描述
Only one prior study has examined the acute influence of cocoa on mental energy. The purpose of this research is to replicate the previous observations and extend research in four ways: 1) start to determine which substance in cocoa responsible for the effect by including several comparison groups, 2) focus on individuals with average or below average symptoms of mental energy and who are not high consumers of fruits, vegetables and other products containing high amounts of flavonoids in order to learn whether people with low energy accrue a greater benefit, and 3) include additional measures of mental energy plausibly influenced by cocoa to better understand the health consequences of cocoa.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 34 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Women and men ages 18-34
- •Lower than average feelings of energy (score of < 13 on Profile of Mood States Vigor scale)
排除标准
- •GI tract disorder
- •Psychoactive medication use
- •Daily consumption of > 200 mg caffeine
- •Body mass index > 30
- •Cigarette smoker
- •Allergy to cocoa, chocolate or caffeine
- •Frequent consumption of cocoa, chocolate-based products or fruits and vegetable containing flavonoids
结局指标
主要结局
Correct Responses on Serial 7 Subtraction Task
时间窗: Pre and 30, 60 and 120 minutes post intervention
Participants subtract the number 7 from a three digit number and quickly and accurately as possible for 60 seconds. The total number of accurate responses is scored. The higher the score the better performance. The range of scores is from a minimum score of 0 to a theoretical maximum score of 120.
Performance on Bakan Task
时间窗: baseline, post 60, post 90, post 120
Performance on Bakan Task at baseline, post-test 1, post-test 2, and post-test 3 Bakan test presents numbers on a computer screen. Participant presses one button whenever the number 6 appears and a different button whenever three odd and different numbers in a row occurs such as 7 5 9. The number of times the participant does this correctly the better the performance. The scores range from 0 to 10 because the sequence of three odd and different numbers occurs a total of 10 times.
次要结局
- Vigor Symptoms (Profile of Mood State)(Pre and 90, 120 and 160 minutes post intervention)
研究者
Patrick O'Connor
Professor of Kinesiology
University of Georgia