Magnetic resonance imaging in early rheumatoid arthritis: The use of a 1.5T extremity scanner in early diagnosis

Recruiting

• Conditions: rheumatoid arthritis; 10023213

• Registration Number: NL-OMON41551
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 800

Inclusion Criteria

- Patients referred with non-traumatic arthritis of at least one joint as confirmed by a medical doctor
- Duration of symptoms less than two years

Exclusion Criteria

- Confirmed septic arthritis or crystal arthropathy
- Routine MRI-contraindications
- Pregnancy
- Renal insufficiency
- Gadolinium contrast allergy

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary study parameters main study<br /><br>- Presence of features of arthritis on MRI, correlated to clinical parameters<br /><br>- Predictive value of MRI for development of RA<br /><br><br /><br>Primary study parameters ultrasound study (amendment)<br /><br>- Presence of US inflammatory features correlated to MR detected (teno)<br /><br>synovitis and clinical parameters. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secundary parameters main study<br /><br>- MRI findings in patients without RA but with an alternative diagnosis (e.g.<br /><br>undifferentiated arthritis, psoriatic arthritis)</p><br>