Role Of MRI In Evaluation Of Rectal Carcinoma.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- 1.To evaluate characteristics of rectal lesion on MRI.
研究概览
简要总结
Carcinoma rectum is a major health concern with increasing incidence globally. Accurate staging is critical for guiding treatment decisions, particularly in distinguishing candidates for neoadjuvant therapy versus direct surgical intervention. This thesis aims to evaluate the diagnostic performance and clinical impact of MRI in staging and restaging rectal carcinoma in patients from Central India. By correlating imaging findings with histopathology and clinical outcomes, this study seeks to highlight the role of MRI as a crucial, non-invasive tool in the multidisciplinary management of rectal cancer in this region. Furthermore, MRI is instrumental in post-treatment evaluation to assess tumor response and detect residual disease or complications.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 1.00 Year(s) 至 90.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients of all age group irrespective of sex will be included.
- •Patients referred with clinical suspicion of rectal carcinoma as part of their clinical evaluation.
- •Patients who have given informed consent for MRI evaluation and inclusion in the study.
排除标准
- •Patient with profuse per rectal bleeding including hemorrhoids.
- •Patients with contraindications to MRI (e.g., pacemakers, cochlear implants, or metallic foreign bodies, claustrophobia)
- •Patients who do not give consent/refusing investigations.
- •Pregnant patients unwilling to undergo MRI.
结局指标
主要结局
1.To evaluate characteristics of rectal lesion on MRI.
时间窗: Outcomes will be assessed at baseline(pre treatment), 4 weeks, 8 weeks, and at final follow up
2.To compare the effectiveness of T2-weighted and diffusion-weighted MRI in staging the primary tumour and regional lymph nodes.
时间窗: Outcomes will be assessed at baseline(pre treatment), 4 weeks, 8 weeks, and at final follow up
3.To assess the accuracy of MRI in predicting mesorectal fascia involvement and resection margin status in rectal cancer.
时间窗: Outcomes will be assessed at baseline(pre treatment), 4 weeks, 8 weeks, and at final follow up
4.To correlate MRI findings with the histopathological diagnosis of rectal lesions.
时间窗: Outcomes will be assessed at baseline(pre treatment), 4 weeks, 8 weeks, and at final follow up
次要结局
未报告次要终点
研究者
Dr Divyakshi Keni
DATTA MEGHE INSTITUTE OF HIGHER EDUCATION AND RESEARCH