Prospective Follow-up of Patients With Chronic Inflammatory Rheumatism

• Conditions: Spondyloarthritis; Inflammatory Disease; Rheumatoid Arthritis

• Registration Number: NCT03076866
• Lead Sponsor: Centre Hospitalier Universitaire de Nice

Brief Summary

It is a prospective follow-up. The aim is to study the maintenance of therapeutic at 10 years and 20 years of inflammatory rheumatism (rheumatoid arthritis and spondyloarthritis)

Detailed Description

All subjects were followed up on a yearly basis collection with clinical data (weight, sex, age, comorbidities, treatment), biological (VS, CRP, ACPA, lipid balance, cross laps), radiology (hand and foot radiographs and ultrasonography ), BMO Measure

Study Timeline

• Study Start: 2001-01-01
• Study First Submitted: 2017-02-23
• Status Verified: 2017-03
• Study First Submitted QC: 2017-03-06
• Study First Posted: 2017-03-10
• Last Update Submitted: 2017-03-13
• Last Update Posted: 2017-03-15
• Primary Completion: 2020-01-01
• Study Completion: 2020-01-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• More than 18 years
• Rheumatoid arthritis meeting ACR criteria Spondyloarthritis meeting ASAS criteria

Exclusion Criteria

• Patient under guardianship

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
therapeutic maintenance at 20 years of follow-up	20 years	All subjects benefit from an annual follow-up including a collection of clinical data (age, sex, weight, comorbidities, swelling and painful joints), biological (CRP, ACPA, cross laps, lipids), radiological, BMO measures (Hologic), and treatments (biological and synthetic DMARDS). Each rheumatologic modification or stop of treatment is transcribed. Therapeutic maintenance definition: modification in rheumatologic treatment (number of DMARDS at 20 years)

Secondary Outcome Measures

Name	Time	Method
evolution of lipidics parameters at 20 years of follow-up	20 years	lipidics parameters ( total, HDL, LDL cholesterol and tryglicerides) are collected each years and modifications/evolution of these parameters will be studied

Trial Locations

Locations (1)

rheumatology department CHU nice; 🇫🇷 Nice, France