PEEP During Induction of Anesthesia in Small Children

Not Applicable

Completed

• Conditions: Pediatric Anesthesia
• Interventions: Other: PEEP; Other: ZEEP

• Registration Number: NCT03540940
• Lead Sponsor: Seoul National University Hospital

Brief Summary

Positive end-expiratory pressure (PEEP) applied during induction of anesthesia prevents atelectasis formation and increases the duration of nonhypoxic apnea in obese and nonobese patients. PEEP also prevents atelectasis formation in pediatric patients. Because pediatric patients arterial desaturation during induction of anesthesia develops rapidly, we studied the clinical benefit of PEEP applied during anesthesia induction.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-05-17
• Study First Submitted QC: 2018-05-17
• Study Start: 2018-05-21
• Study First Posted: 2018-05-30
• Status Verified: 2019-08
• Primary Completion: 2019-08-14
• Study Completion: 2019-08-14
• Last Update Submitted: 2019-08-14
• Last Update Posted: 2019-08-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• pediatric patients undergoing general anesthesia using endotracheal intubation

Exclusion Criteria

• previous history of lung disease
• anticipated difficulty in airway management

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Positive end expiratory pressure	PEEP	-
zero positive end expiratory pressure	ZEEP	-

Primary Outcome Measures

Name	Time	Method
Duration of Apnea	from the start of apnea until SpO2 reached 95%, maximum 5 minutes.

Trial Locations

Locations (2)

Hee-Soo Kim; 🇰🇷 Seoul, Soul-t'ukpyolsi, Korea, Republic of

Seoul National University Hospital; 🇰🇷 Seoul, Korea, Republic of