Causes and Clinical Outcomes of Acute Kidney Injury After Cardiac Arrest: A Retrospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 82
- 试验地点
- 1
- 主要终点
- Acute Kidney Injury (AKI)
研究概览
简要总结
The development of AKI (Acute Kidney Injury) after cardiac arrest is a common factor associated with mortality. In this study, we aimed to evaluate the factors that increase the risk of developing AKI after cardiac arrest.
For the study, patients were evaluated for the incidence of acute kidney injury (AKI), factors that increase the risk of AKI, and the impact of AKI on mortality. In this process, demographic data, comorbidities, hemodynamic data, laboratory data, clinical symptoms and findings recorded in the electronic decision support system were recorded and analyzed.
详细描述
This retrospective study was performed on patients hospitalized in intensive care units after cardiac arrest between 2013 and 2022. Patients who met the inclusion criteria were included in the study. Urea, creatinine values, and whether AKI was diagnosed or not were obtained from the data registry system. Statistical evaluation was performed using univariate binary logistic regression analysis.
Demographic data, location of cardiac arrest (in-hospital, out-of-hospital), and duration of CPR were recorded. In addition, the causes of cardiac arrest, HR/MAP (heart rate/average arterial pressure) ratio, and whether VSP (vasopressor) or INO (inotropic) medication was needed were recorded.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult patients with spontaneous circulation after cardiac arrest and admitted to the intensive care unit
排除标准
- •Deaths in the first 48 hours
- •Missing data
- •End stage CKD or first day hemadsorption
- •CPR time <3 min
- •Unwitnessed cardiac arrest
- •Terminal malignancy
- •90 years old
- •Having a pace marker
- •Massive bleeding
- •ECMO application
- •First day diyabetes insipitus
结局指标
主要结局
Acute Kidney Injury (AKI)
时间窗: Within 48 hours after intensive care unit admission
Creatinine values in the first 48 hours of intensive care unit admission after cardiac arrest
次要结局
- Mortality(Clinical and laboratory data within 48 hours after intensive care unit admission will be used)
- AKI incidence(Within 48 hours after intensive care unit admission)