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effect of sildenafil citrat on endometrial thickness

Not Applicable
Not yet recruiting
Conditions
infertility.
Female infertility
Registration Number
IRCT20210216050385N1
Lead Sponsor
Dezfoul University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Female
Target Recruitment
72
Inclusion Criteria

Infertile women between 39-18 years
All women who have a frozen fetus and have a history of a thin endometrium routinely prescribed medication to prepare the endometrium
The condition of the fetus returned from the freez should be have a good quality (grade A-B)
Lack of drug sensitivity

Exclusion Criteria

History of endocrine disease: Diabetes - Hyperthyroidism - Hyperprolactinemia
History of hysteroscopic surgery due to intrauterine adhesions
specific cardiovascular disease
History of stroke or myocardial infarction
serious hapeatofailure or renal failure
Alcohol abuse or substance abuse
Use of donated ovum
PCOS
endometriosis

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Clinical pregnancy. Timepoint: Three to four weeks after embryo transfer. Method of measurement: Presence of pregnancy sac in vaginal ultrasonography.;Chemical pregnancy. Timepoint: 2 weeks after embryo transfer. Method of measurement: serologic labratory result BHCG=25.;Endometrial thickness. Timepoint: From the eleventh day of the menstrual cycle serially every other day. Method of measurement: vaginal ultrasonography.
Secondary Outcome Measures
NameTimeMethod
Transmitted fetal quality. Timepoint: transmition day. Method of measurement: In terms of quality, it is divided into one of 3 groups A, B and C based on the number and size of embryonic cells (blastomers), increasing the pervasiveness and presence of multinucleated cells.;Implantation rate. Timepoint: Two weeks after embryo transfer. Method of measurement: beta-HCG examination.
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