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Clinical Trials/NCT04078802
NCT04078802
Unknown
Not Applicable

Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) Compared With Traditional Vaginal Utero-sacral Ligament Suspension for Vaginal Apex Prolapse

Rambam Health Care Campus0 sites60 target enrollmentOctober 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Vaginal Prolapse
Sponsor
Rambam Health Care Campus
Enrollment
60
Primary Endpoint
surgery time
Last Updated
6 years ago

Overview

Brief Summary

VNOTES (Transvaginal natural orifice transluminal endoscopic surgery) is a relatively new surgery for Hysterectomy and Uterosacral ligament suspension to treat Vaginal prolapse. The investigators wish to run a randomized control trial comparing it to classic Vaginal hysterectomy for the same indication.

Detailed Description

The investigators will recruit 60 women with indication for surgery to treat uterine prolapse. 30 women will undergo VNOTES surgery and 30 women will undergo classic vaginal hysterectomy. The investigators will compare outcomes of the surgeries such as surgery time, bleeding and clinical outcomes after 3 and 6 months post operation.

Registry
clinicaltrials.gov
Start Date
October 2019
End Date
November 2020
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Omer MOR MD

Principle Investigator

Rambam Health Care Campus

Eligibility Criteria

Inclusion Criteria

  • women with vaginal prolapse
  • capable of having a surgery - assessed by an anesthesiologist
  • women who approve of having the surgery

Exclusion Criteria

  • BMI over 40
  • women who have recurrent PID (pelvic inflammatory disease)
  • women with oncology records

Outcomes

Primary Outcomes

surgery time

Time Frame: from admission up to 6 hours post operation

time of surgery

Secondary Outcomes

  • PFDI score - Pelvic Floor Disability Index(from admission up to 6 hours post operation)
  • hospital days(from admission up to 96 hours post operation)
  • PISQ12 score - Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire(from admission up to 6 hours post operation)
  • bleeding(from admission up to 6 hours post operation)

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