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Clinical Trials/NCT04240730
NCT04240730
Completed
Not Applicable

Transvaginal Natural Orifice Endoscopic Surgery (v-NOTES) for Extremely Obese Patients With Early-stage Endometrial Cancer

Dr. Lutfi Kirdar Kartal Training and Research Hospital1 site in 1 country6 target enrollmentJanuary 1, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Endometrial Cancer
Sponsor
Dr. Lutfi Kirdar Kartal Training and Research Hospital
Enrollment
6
Locations
1
Primary Endpoint
Pre- and post-operative hemoglobin levels
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The aim of this study is to investigate the feasibility and efficacy of the v-NOTES approach for extremely obese patients with early-stage type 1 endometrial cancer.

Registry
clinicaltrials.gov
Start Date
January 1, 2019
End Date
June 30, 2019
Last Updated
6 years ago
Study Type
Observational
Sex
Female

Investigators

Sponsor
Dr. Lutfi Kirdar Kartal Training and Research Hospital
Responsible Party
Principal Investigator
Principal Investigator

Emre Mat

Head of Gynecologic Oncology

Dr. Lutfi Kirdar Kartal Training and Research Hospital

Eligibility Criteria

Inclusion Criteria

  • Extreme obese patients
  • Early stage type-1 endometrial cancer proved by endometrial sampling

Exclusion Criteria

  • any contraindication for pneumoperitoneum
  • any contraindication for the dorsal lithotomy position
  • any contraindication for general anesthesia,
  • any contraindication for v-NOTES
  • suspicion of pelvic adhesions
  • presence or suspicion of obliteration of the pouch of Douglas

Outcomes

Primary Outcomes

Pre- and post-operative hemoglobin levels

Time Frame: 24 hours

Hemoglobin levels in g/dL. Hemoglobin levels of the patients before surgery and on postoperative day 1.

Any conversion to conventional laparoscopy or laparotomy

Time Frame: 4 hours

Number of the patients whose surgery couldn't completed by transvaginal natural orifice surgery.

Operating time

Time Frame: 4 hours

The operation time in minutes. The operation time was from commencement of the colpotomy incision to vaginal closure.

Length of hospital stay

Time Frame: 2 day

Length of hospital stay in days. Duration of hospital stay was calculated from the patient's admission until hospital discharge.

Any intra- or post-operative complication

Time Frame: 6 months

Number of the patients who have any complication during or after transvaginal natural orifice surgery.

pain scores

Time Frame: 24 hours

Pain scores in VAS score. Pain scores were evaluated using a visual analog scale (VAS). Scores are based on self-reported measures of pain that are recorded with a single handwritten mark placed at one point along the length of a 10-cm line that represents a continuum between the two ends of the scale-"no pain" on the left end (0 cm) of the scale and the "worst pain" on the right end of the scale (10 cm).

Study Sites (1)

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